|本期目录/Table of Contents|

[1]林志群,赵大川,郎敏,等.载纳米银海藻酸钙敷料的制备及体外细胞毒性、抗菌性能的检测[J].生物医学工程研究,2016,02:113-117.
　LIN Zhiqun,ZHAO Dachuan,LANG Min,et al.Study on Preparation ,Cytotoxicity and Antibacterial Capacity of Calcium Alginate Loaded with Silver Nanoparticles[J].Journal of Biomedical Engineering Research,2016,02:113-117.
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载纳米银海藻酸钙敷料的制备及体外细胞毒性、抗菌性能的检测(PDF)

《生物医学工程研究》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2016年02期
页码:
113-117
栏目:
出版日期:
2016-06-25

文章信息/Info

Title:
Study on Preparation ,Cytotoxicity and Antibacterial Capacity of Calcium Alginate Loaded with Silver Nanoparticles
文章编号:
1672-6278 (2016)02-0113-05
作者:
林志群; 赵大川; 郎敏; 柳学文; 陈瀛; 陈飞; 黄宗海△
南方医科大学珠江医院普通外科，广州 510280
Author(s):
LIN Zhiqun;  ZHAO Dachuan;  LANG Min; LIU Xuewen; CHEN Ying; CHEN Fei;  HUANG Zonghai
Department of General Surgery,Southern Medical University Zhujiang Hospital,Guangzhou510280,China
关键词:
纳米银; 海藻酸钙; 物理学表征; 细胞毒性; 抗菌性能
Keywords:
AgNPs;  Calcium alginate;  Characterization;  Cytotoxicity;  Antibacterial
分类号:
R318
DOI:
-
文献标识码:
A
摘要:
以湿法纺丝法制得的海藻酸钙羧甲基纤维复合物作为敷料载体，再利用浸渍法将纳米银粒子搭载于敷料之上，制备质量分数为0.5、1、2、4%的载纳米银海藻酸钙抗菌敷料。采用紫外-可见光分光光度计和扫描电子显微镜检测敷料的物理学表征，并检测抗菌敷料的细胞毒性及抗菌性能。结果表明载纳米银海藻酸钙抗菌敷料表面可见纳米银均匀附着，于去离子水中可释放纳米银粒子，而载银量1%的海藻酸钙敷料无明显细胞毒性且对常见四种菌株均有良好的抗菌性能，是一个理想的载银浓度。
Abstract:
Calcium alginate-Carboxymethyl cellulose complex , made by wet spinning , was loaded with silver nanoparticles by impregnation method .By this way，0.5、1、2、4% AgNPs-Ca(w/w) dressing were prepared . UV-Vis and SEM were used to detect the physical characterization of AgNPs-Ca .The in vitro cytotoxicity and antibacterial capacity of AgNPs-Ca were tested . The results showed that AgNPs sticked to the surface of AgNPs-Ca evenly , which may release AgNPs freely in deionized water . It is confirmed that 1% AgNPs-Ca has strong antibacterial property without any cytotoxicity , and 1% is considered as a ideal concentration in AgNPs addition.

参考文献/References

备注/Memo

备注/Memo:
收稿日期：2016-02-19广州市海珠区科技计划项目(2013-cg-27)通信作者Email:drhuangzh@163.com
更新日期/Last Update: 2016-07-04