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Title:: Analysis on the consistency of extremely short-term heart rate variability and pulse rate variability

作者:: 彭敏1; 何宝林2; 刘静3; 于璐1△; 1.中国医科大学公共基础学院生物医学工程系，沈阳 110122；2.中国医学科学院血液病医院(中国医学科学院血液学研究所)实验血液学国家重点实验室国家血液病临床医学研究中心，天津 300020;3.武汉大学中南医院核医学科，武汉 430071

Author(s):: PENG Min1; HE Baolin2; LIU Jing3; YU Lu1; .Department of Biomedical Engineering, School of Fundamental Sciences, China Medical University ，Shenyang 110122,China;2.State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China;3.Department of Nuclear Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071,China

Keywords:: Extremely short-term; Consistency analysis; Heart rate variability; Pulse rate variability; Sleep apnea; Automatic nervous system

摘要:: 本研究利用多导睡眠仪采集呼吸暂停、快速呼吸、慢速呼吸和平静呼吸四种状态下的心电、脉搏信号，来进行极短时15 s的心率变异性与脉率变异性六个指标计算。通过Bland-Altman一致性分析图与散点图、单样本K-S检验、Mann-Whitney U检验、Pearson相关性系数来比较心率与脉率的一致性程度，结果显示，MEAN，Lomb-nLF, Lomb-nHF, Lomb-nLF/nHF,DFA1五个指标在四个状态下具有较好的一致性。因此，可以用极短时内的脉率变异性来替代心率变异性，以反映自主神经功能变化。

Abstract:: We used the polysomnography to collect the electrocardiogram and Oxygen saturation of four breathing states (apnea, fast breathing, slow breathing, calm breathing) to perform heart rate variability and pulse rate variability for a very short 15 s index calculation.Through the Bland-Altman consistency analysis chart and scatter plot, one-sample K-S test, Mann-Whitney U test, Pearson correlation coefficient, the consistency of heart rate and pulse rate was compared. The results showed that the five indicators of MEAN, Lomb-nLF, Lomb-nHF, Lomb-nLF/nHF, and DFA1 had good consistency in the four states. The extremely short-term pulse rate variability can to replace heart rate variability to reflect the changes of autonomic nerve function.