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Title:: Design of waterless cooling microwave ablation needle based on vacuum tube

Author(s):: LI Junle; YANG Jin; QIAN Zhiyu; （College of Automation Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 211106, China）

Keywords:: Microwave ablation; Vacuum tube; Waterless cooling microwave ablation needle; Finite element; Simulation

摘要:: 为减少组织碳化，提高微波消融治疗的有效性，本研究根据现有水冷法的原理，设计了一款基于双层不锈钢真空管的无水冷微波消融针。利用离体猪肝实验,验证了真空管隔热的有效性；根据有限元仿真方法建立了微波消融仿真模型，并通过实验验证，达到了更好的消融效果。仿真和实验结果表明，无水冷真空管微波消融针无消融尾迹；与传统带水冷的消融针相比，在相同剂量下，无水冷真空管可得到更大的消融区域和更小的碳化区域。本研究证明了真空管用于无水冷消融的可行性，可为后续设计微波消融针提供新的思路。

Abstract:: In order to reduce tissue carbonization, improve the effectiveness of microwave ablation therapy. Based on the principles of existing water-cooling methods, a waterless cooling microwave ablation needle using a double-layer stainless steel vacuum tube was designed. The effectiveness of vacuum tube insulation was verified through ex vivo pig liver experiments. A microwave ablation simulation model was established by using finite element simulation methods, and experimental validation was conducted, resulting in improved ablation effectiveness. Simulation and experimental results indicated that the waterless cooling vacuum tube microwave ablation needle did not exhibit ablation residues. Compared to traditional water-cooled ablation needles, it could achieve a larger ablation area and a smaller carbonization area at the same dosage. This research demonstrate the feasibility of using a vacuum tube for waterless cooling ablation and provide new insights for the subsequent design of microwave ablation needles.